Metachronous tumors in a patient with Fanconi’s anemia: case report
Tumores metacrônicos em paciente portadora de Anemia de Fanconi: relato de caso
Luis Eduardo Silva Móz, Daniele Tramontina, Mariana Cartaxo Alves, Natália Helena Valleta, Renan Sordi, Renata Tortato Meneguetti, Cláudia Vaz de Melo Sette, Daniel de Iracema Gomes Cubero, Auro del Giglio
Abstract
We present the case of a patient who entered early menopause at age 29 and was diagnosed with two primary tumors, bladder cancer at age 30 and esophageal cancer at 36. She has family history of cancer, since her brother had esophageal cancer at age 29. Given her clinical status, we hypothesized Fanconi anemia, which was diagnosed by the diepoxybutane (DEB) test. The literature contains few case reports on the association between Fanconi anemia and esophageal cancer, and only one regarding its association with bladder cancer.
Keywords
Resumo
Apresentamos um caso de uma paciente que teve menopausa precoce aos 29 anos e foi diagnosticada com dois tumores primários, sendo câncer de bexiga aos 30 anos e câncer de esôfago aos 36 anos. Ela também possui antecedente familiar oncológico, pois o seu irmão teve câncer de esôfago aos 29 anos. Frente ao quadro clínico, aventada a hipótese de Anemia de Fanconi, confirmada pelo DEB teste. Há poucos casos relatados na literatura de associação entre Anemia de Fanconi com câncer de esôfago, sendo encontrado apenas um relato da associação com câncer de bexiga.
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Referências
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